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doi: 10.1038/s41467-022-31772-9 204 LiuJTangDKangR

Emerging evidence demonstrates that tumor cells possess the ability to sense and interpret these signals through mechanosensors and mechanotransducers, including mechanosensitive ion channels (e.g., ion channels that belong to the transient receptor potential (TRP) family), ion transporters, focal adhesions, cytoskeletal elements, nuclear proteins, and transcription factors

Shigeto M, Ramracheya R, Tarasov AI et al (2015) GLP-1 stimulates insulin secretion by PKC-dependent TRPM4 and TRPM5 activation