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Wegovy (semaglutide) is a once-a-week injection thats approved by the Food and Drug Administration (FDA) to: Reduce excess body weight and maintain weight reduction in: Adults with a body mass index (BMI) of 30 or higher Adults with a BMI of 27 or higher who also have weight-related medical problems, such as high cholesterol or high blood pressure Adolescents ages 1217 who are at or above the 95th percentile on sex- and age-specific growth charts Reduce the risk of major adverse cardiovascular events in adults with established cardiovascular disease and a BMI of 27 or higher Wegovy belongs to a family of drugs called glucagon-like peptide-1 (GLP-1) receptor agonists)

Effects of glucagon on H + -HCO3 transport in Henles loop, distal tubule, and collecting ducts in the rat

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