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The researchers found that patients who gained or maintained weight while on a GLP-1 receptor agonist were more likely to lose weight after switching to phentermine, with a median weight loss of around 3% in the year after GLP-1 discontinuation

Consistent with the effects in rat PSCs, high glucose and TGF1 levels enhanced the proliferation and decreased the apoptosis of PSCs in the LG group, whereas GSH and SB431542 prevented the effects induced by high glucose

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