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Our findings highlight the potential beneficial effects of activated AMPK and mTOR pathways by creatine treatment specifically in improving muscle endurance and swim speed in the LMNA (R453W) fish, yet the beneficial effects by l-carnitine treatment in LMNA (L35P) fish did not rely on the AMPK and mTOR pathways, which needs further experiments to identify its potential underlying mechanism
Of course, rats are not people
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