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Nanomedicine Nanotechnology, Biol Med
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The blood pressure-lowering effect appears to be driven primarily by weight loss (patients in the STEP trials lost 10-15% of body weight), though improvements in insulin sensitivity and vascular function may also contribute
These numbers represent averages from clinical trials involving participants who adhered to the full treatment protocol
If you experience hypoglycaemia (particularly if you also take insulin or sulfonylureas), take 15-20g of fast-acting carbohydrate, recheck after 15 minutes, and follow with a longer-acting carbohydrate if needed
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![Mechanism of action of GLP-1 [25]](https://www.researchgate.net/publication/256289222/figure/fig1/AS:614177232142337@1523442671231/Mechanism-of-action-of-GLP-1-25.png)
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