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annulata -infected macrophages (TaC12) were maintained in L15 medium (Gibco, Thermo Fisher Scientific, Waltham MA, USA), while uninfected bovine macrophages (BoMac) 64 and human embryonic kidney cells (HEK293FT) were grown in DMEM medium (Gibco)

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The results ranked their contributions in descending order as follows: Moheibacter , L-carnitine, Gaetbulibacter , N,N,N-trimethyllysine, alpha-linolenic acid, betaine, Cnuella , Lacibacter , and MPO