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The extent to which TB-500 reproduces the clinical effects of the full protein remains an open research question

Specific Populations Pediatric Patients The pharmacokinetics and pharmacodynamics (glucosuria) of dapagliflozin in pediatric patients aged 10 to 17 years with type 2 diabetes mellitus were similar to those observed in adult patients with same renal function

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the original Raun 1998 pharmacology paper established its hallmark profile of GH release without ACTH, cortisol, or prolactin elevation