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Variants in FTO (linked to appetite regulation and adiposity set-point), GLP1R (the GLP-1 receptor gene), MC4R (a melanocortin receptor central to energy balance), and TCF7L2 (tied to glucose homeostasis and GLP-1 secretion) map the terrain a clinician prescribes into

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Your healthcare provider may arrange blood tests to exclude other causes of fatigue, including full blood count (to check for anaemia), thyroid function tests, vitamin B12 and folate levels, vitamin D status, renal and liver function, and HbA1c to assess diabetes control

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