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Could it possibly be the B vitamins

In addition to promoting weight loss up to 20.9% in clinical trials, tirzepatide: Reduces visceral fat and improves insulin sensitivity-even in non-diabetic individuals Inhibits inflammatory cytokines like TNF- and IL-6 Shifts immune profiles toward anti-inflammatory M2 macrophages Stimulates thermogenesis by boosting UCP1 expression in brown adipose tissue Reduces fibrosis by modulating extracellular matrix remodeling These effects mirror many of the pathological mechanisms at play in lipedema

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