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When a study microneedles a copper-peptide solution into the scalp and observes regrowth, the needling itself is a confound: some or all of the benefit may come from the mechanical stimulus rather than the peptide

Discussion In this model-based analysis of phase III randomized trials in individuals with T2DM, we observed that semaglutide and tirzepatide exhibit broadly comparable pharmacodynamic profiles for weight reduction when evaluated across clinically relevant dose ranges