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C., Song, S., Li, Y

GLP-1 binds to GLP-1Rs expressed in multiple organs, including the pancreas, liver, gastrointestinal tract and brain, exerting pleiotropic effects such as enhancing insulin secretion (18), reducing blood glucose levels, suppressing GCG release (19), delaying gastric emptying (16), decreasing food intake (20), promoting weight loss and providing cardiovascular protection (21,22)

While minor volume may return if weight is regained, most patients require targeted aesthetic treatments to restore facial balance and firmness

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