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According to FDA prescribing data , nausea affects up to 20% of patients on semaglutide, while vomiting and diarrhoea affect roughly 8% to 12%

Based on these results, semaglutide is expected to be submitted to FDA for MASH in 2025, potentially becoming the first GLP-1 RA officially approved for MASH

In 2024, Wegovy also received FDA approval to reduce the risk of cardiovascular death, non-fatal myocardial infarction, and non-fatal stroke in adults with established cardiovascular disease and either obesity or overweight