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SGLT1, which is predominantly expressed in the intestines is also expressed in the kidneys, is a high-affinity, low-capacity glucose transporter in the proximal tubules, which makes a minor contribution to the reabsorption of filtered glucose (approximately 10%) (22,139)

Clinical data shows 91% of patients maintain reduced sugar intake at 12 months, with HbA1c improvements averaging 2.1% in diabetic participants

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