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Chronic GLP-1 receptor activation by exendin-4 induces expansion of pancreatic duct glands in rats and accelerates formation of dysplastic lesions and chronic pancreatitis in the KrasG12D mouse model

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Pre-existing conditions: Some drugs (e.g., GLP-1 analogs, DPP-4 inhibitors) are mainly used by diabetic patients, and diabetes is an independent risk factor for pancreatitis ( 5 Conclusion In summary, disproportionality analysis helped to identify 101 from 867 drugs with pancreatitis report number 3 in 64,866 reports, and network pharmacology analysis investigated the toxicological mechanisms of 50