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[DOI] [PMC free article] [PubMed] [Google Scholar] 80.Giovannucci E., Harlan D.M., Archer M.C., Bergenstal R.M., Gapstur S.M., Habel L.A., Pollak M., Regensteiner J.G., Yee D

Notably, both aging and zinc deficiency are associated with an increased number of macrophages [217, 218] and monocytes [167, 172, 219, 220]

Limitations Even though we strove to be as biologically detailed and unbiased as possible, we had to refine weakly constrained parameters due to limited available data and focus on the most relevant pathways and processes rather than simulating dynamics at the whole genome-scale

These changes suggest that enamel is thinning or eroding