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Cellular Dysregulation: since MOTS-c affects fundamental metabolic processes, unintended consequences could occur if dosing is uncontrolled

Since low level reactive oxygen species (ROS) signaling is important for normal cellular function, full suppression of ROS may be harmful or otherwise alter normal intracellular signaling [2]

This phased approach is designed to systematically transition from computational mRNA-based findings to a clinically applicable protein-level diagnostic tool

Association between anti-ZnT8 autoantibody specificities and SLC30A8 Arg325Trp variant in Japanese patients with type 1 diabetes