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Community protocols and trial storage documentation describe avoiding freeze-thaw cycles on reconstituted vials freeze-thaw cycles are the documented cause of peptide structure damage

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Gel-forming antioxidant eye drop efficacy in rats To determine whether NAC or NACET in the gel-forming eye drop vehicle would provide protection of photoreceptor structure and function in vivo, we performed once daily dosing for a total of 3 doses prior to intravitreal PQ injection, then continued once daily administration for 7 doses after induction of retinal degeneration in Brown Norway rats