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Interestingly, improvements in glucose metabolism were observed in two studies that reported decreased oxidative stress markers (6, 23)
Low levels of B12 can lead to hyperpigmentation, vitiligo, pale or jaundiced skin, and premature signs of aging like fine lines and wrinkles
Stromal cells Cancer-associated fibroblasts (CAFs) are essential components of the TME with multiple roles, encompassing stromal remodeling and deposition, extensive bidirectional signaling interactions with cancer cells, and communication with immune cells
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