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A vial sitting in direct sunlight on a car dashboard, even for 20 minutes, can experience temperatures well above 40 degrees Celsius

It is shown to be increasing dopamine-B-hydroxylase levels, decreasing extracellular dopamine release, increasing DAT surface expression, increasing dopamine turnover, and suppressing projections to NAc, GLP-1R agonists might be decreasing palatable food or drug-induced phasic dopaminergic signaling in reward-related areas and therefore decreasing conditioned consummatory behavior

doi:10.1210/mend.12.8.0153

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