These changes are more likely linked to weight loss or other health factors rather than a direct effect of the medicine
doi: 10.3389/fendo.2025.1650729 Received 20 June 2025 Accepted 18 September 2025 Published 01 October 2025 Volume 16 - 2025 Edited by Maria Gazouli, National and Kapodistrian University of Athens, Greece Reviewed by Xiaohang Wang, Affiliated Hospital of Yangzhou University, China Junqing Lin, Shanghai Jiao Tong University, China Guangda He, Chinese Academy of Medical Sciences and Peking Union Medical College, China Updates Copyright 2025 Niu, Chen, Wu, Wang, Xu, Yin and Zhao
GnRH, CYP19a1b decrease in a dose-dependent manner due to endocrine disrupting and xenoestrogenic effect of 4-NP exposure of 64 g/L as a low dose and 160 g/L as a high dose given for the period of 30 days and 60 days of exposure
Those lower doses are adjusted for an average difference in body weight, which would require men to take larger quantities and spend more to make up for it when compared to products from Swolverine and others