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This is a concern, particularly for those trying to improve their overall body composition or for individuals with diabetes, where muscle mass plays a vital role in insulin sensitivity

Acne can fluctuate due to numerous factors including stress, hormonal cycles, skincare products, environmental conditions, and other medications

Although prospective studies specifically targeting PCOS + MASLD with pregnancy outcomes as the primary endpoint are currently lacking, a robust inference can be drawn based on the pathophysiological framework of MASLD and evidence from the general population: proactively identifying and reducing MASLD and ectopic fat load prior to pregnancy may be a key step in improving both periconception outcomes and long-term prognosis (68, 76)