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An fMRI study in obese individuals also reported a normalised brain response to food cues when treated with the GLP1RA exenatide [125]

Key points about Wegovy dosing: Administered once weekly via subcutaneous injection Should be taken on the same day each week Can be given at any time of day, with or without meals Injection sites include abdomen, thigh, or upper arm Consistent timing supports treatment effectiveness and helps establish a sustainable routine While Wegovy is licensed for adults with a BMI 30 kg/m (obesity) or 27 kg/m with weight-related comorbidities, NHS availability through specialist weight management services follows NICE guidance (TA875), which has specific eligibility criteria including BMI thresholds (with ethnicity adjustments) and prior interventions