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The removal of biotin from lysine residues in proteins in the diet and from the carboxylases in cells, through the action of biotinidase, and then the incorporation of the biotin into the carboxylases, through the action of holocarboxylase synthetase, is referred to as the biotin cycle

This hormonal disruption likely contributes to changes in peripheral lymphocyte levels and immune function markers in anorexia nervosa

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