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In: Kelloff GJ, Hawk ET, Sigman CC, eds

Obestatin treatment causes a reduction in Pit-1 and GHRH-R mRNA levels in the pituitary as well as a decrease in hypothalamic GHRH and ghrelin expression

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Neither hormone should be taken as an over-the-counter therapy their administration requires regular blood testing and should be under the control of an experienced endocrinologist