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Mechanistic (cytokine/NF-B) signals exist, but molecular targets are unknown and immunogenicity is unassessed

doi:10.1111/bph.14396 Hanning N, De Bruyn M, Ceuleers H, et al

On the other hand, excessive drug intake reduces executive function through dysregulated glutamatergic, GABAergic, and dopaminergic networks in the prefrontal cortex (PFC), which results in compulsive drug use [5]

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