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Issa Dahabreh reported a contract with the Patient-Centered Outcomes Research Institute and grants from the National Institutes of Health during the conduct of the study

Sarah Casella Katelyn Galli Introduction: While glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have become increasingly prescribed, use is often inhibited by the gastrointestinal adverse effects that patients must endure

Its main symptoms include acid regurgitation, heartburn, chest pain, and cough, with some patients also experiencing dysphagia and hoarseness

The compound consists of 39 amino acids and is structurally engineered for enhanced stability and once-weekly subcutaneous injection due to its extended half-life of approximately six days