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For some people, cannabis provides relief from chronic pain and anxiety, while others find it helpful for stimulating appetite or promoting relaxation

doi: 10.1016/j.psyneuen.2014.09.025

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The protein encoded by the CTLA4 gene is also involved in regulating T cell activation and like polymorphisms in the PTPN22 gene, polymorphisms in CTLA4 are associated with other autoimmune disorders such as Addison disease and Graves disease