glp-1 medullary thyroid cancer GLP1 medications have led to increased risk of in rodents and therefore should not be used in those with a personal or family history of medullary thyroid cancer or MEN2 Assessing Thyroid Cancer Risk With

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Additional common gastrointestinal effects during early treatment include: Diarrhea (affecting 18-24% of patients) usually begins within the early weeks of treatment Constipation (occurring in 16-17% of patients) can develop as gastric motility decreases Vomiting (reported by 8-10% of patients) typically accompanies more severe nausea episodes Abdominal pain or discomfort (affecting 6-10% of patients) often described as cramping or bloating Decreased appetite (experienced by 6-10% of patients) usually noticeable within the first few days Dyspepsia (indigestion) and eructation (belching) additional common digestive symptoms Beyond gastrointestinal symptoms, some patients experience injection site reactions including redness, itching, or mild swelling at the administration site

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Pentoxifylline modifies three-dimensional collagen lattice model contraction and expression of collagen types I and III by human fibroblasts derived from post-burn hypertrophic scars and from normal skin