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The optimal frequency, duration, and total number of courses for humans is entirely unknown

(141) further confirmed in 2023 that the H 2 S donor GYY4137 improves renal oxidative damage in diabetic mice by decreasing NADPH oxidase 2 (NOX2) expression and increasing heme oxygenase-2 (HO-2) and paraoxonase 1/2 (PON1/2) expression

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