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33,34 In this regard, glucagon-like peptide-1 (GLP-1) is one of the incretins with a pivotal role in many aspects of glucose regulation in the gutbrain axis because its receptor, the GLP-1 receptor (GLP-1R), is expressed not only in the pancreas but also widely in the periphery (such as in the lung, stomach, intestine, kidney, and heart) as well as most regions of the brain

Because postmenopausal women on hormone therapy combined with GLP-1s often achieve significantly greater weight loss than those on GLP-1s alone, AI models could track symptoms alongside metabolic markers and help determine the optimal dosage of the GLP-1 to use in conjunction with hormone therapy, maximizing the benefit of both

doi: 10.1084/jem.20061287 76 WangYWangWShenCWangYJiaoMYuWet al