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TMA is generated by gut bacteria when they metabolize choline, lecithin (phosphatidylcholine), and L-carnitine [2, 3]

The clinical trial data is specifically reassuring on this point: across six trials involving approximately 900 participants, glucose levels, insulin levels, and markers of insulin sensitivity remained unchanged from baseline

Both peptides have documented immunomodulatory activity: Epitalon pineal-immune axis: melatonin is a potent immunomodulator, and melatonin restoration in aged animals is associated with improved NK cell cytotoxicity, T-cell proliferative responses, and reduced pro-inflammatory cytokine baseline (TNF-, IL-6)

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