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Interestingly, suppressing the ER stress pathway PERK-ATF4-CHOP did not affect CHAC1 expression during ferroptosis ( As controlled induction of ferroptosis might prove a promising target for cancer research, various pharmacological substances have been tested for possibly inducing ferroptosis

It binds circulating iron and intracellular iron, stabilizing the level of iron in cardiac tissue, also clearing cardiac iron and reducing myocardial oxidative stress in Fe overload in vitro (Jansov and imnek 2019)

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