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Major drug Interactions: The pressor effect of sympathomimetic pressor amines is markedly potentiated in patients receiving monoamine oxidase inhibitors (MAOIs) References: Alhashemi JA (2002): Reduction of vasopressor requirement by hydrocortisone administration in a patient with cerebral vasospasm

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In vivo validation of hits using retroductal injection Based upon drug down selection data and measured EC 50 values, Phenylbutazone, Enoxacin, and Doripenem hydrate were selected for in vivo validation in mice using H2AX foci per nucleus IHC staining as an outcome measure consistent with prior work showing correlation with the development of xerostomia (Supplementary Fig

Glucagon-like peptide-1 receptor agonists for treatment of nonalcoholic fatty liver disease and nonalcoholic steatohepatitis: an updated meta-analysis of randomized controlled trials