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Case reports that linked GLP-1s to suicidality have raised regulatory concerns and left many wondering if these medications are harming the patients they intend to help, Laurent Azoulay, PhD , a professor and William Dawson Scholar at McGill University and a senior investigator at the Jewish General Hospitals Lady Davis Institute in Montreal, Canada, told Healio

On a day-to-day basis, our bodies are equipped to manage oxidative stress, however, with regular and excessive alcohol consumption, our body cannot keep repairing the damage leading to a state of oxidative stress

One theory is that GLP-1 activation increases pancreatic secretion and ductal pressure

The SURMOUNT-1 trial studied the effects of tirzepatide in adults with obesity and found: People taking 5 mg of tirzepatide lost about 15% of their body weight