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In women with PCOS, circulating levels of inflammatory markers such as C-reactive protein (CRP), interleukin-6 (IL-6), and tumor necrosis factor- (TNF-) are significantly elevated ( 2.5 Environment and lifestyle Environmental exposures and lifestyle choices significantly influence PCOS risk

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This activity supports cytosolic redox balance, particularly under high glycolytic flux, and contributes to energy metabolism and reactive oxygen species (ROS) generation in metabolically active tissues 55