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However, even a 50% reduction in worm burden would decrease the human health problems caused by schistosomiasis, and a combination of auranofin (or another TGR inhibitor) with an agent that works by a different mechanism might be more effective and would also reduce the chances of the parasite developing drug resistance

Cells were passaged when they reached 7080% confluence, again maintaining 30 10 6 cells at each serial passage, with 5FU added in fresh media every 3 days

A consultation before starting is the safest way to confirm you are a good candidate

The reported value for K m of -GCS for cysteine is 0.35 mM (Richman and Meister, 1975)