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doi: 10.4161/trns.22281 43 FrancetteA

AHK-Cu delivers copper ions as enzymatic cofactors for lysyl oxidase (collagen cross-linking) and superoxide dismutase (antioxidant defense), rather than binding to cell surface receptors like GLP-1 agonists, growth hormone secretagogues, or melanocortin receptor peptides

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Mechanistically, quercetin may also enhance glucose uptake by regulating the expression and function of GLUT4 and the insulin receptor beta subunit ( FIGURE 3 On the other, hyperglycemia also induces metabolic alterations, resulting in the disturbance of protein, fat, and carbohydrate metabolism