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The gut-brain axis has emerged as a compelling frontier in neuroprotection, characterized by complex bidirectional communication between the CNS, the enteric nervous system, and the intestinal microbiota

Sedating Antihistamines (Diphenhydramine/Doxylamine) Mechanism: Antihistamines block H1 receptors, causing drowsiness

Here, we evaluate the effects of TSS pathway activation through cystathionine beta-synthase (CBS) to attenuate reactive oxygen species (ROS) and ferroptosis stresses in SCD