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Genome-wide association analyses have detected critical polymorphisms in genes regulating hepatic lipid handling, including patatin-like phospholipase domain-containing 3 (PNPLA3) and transmembrane 6 superfamily member 2 (TM6SF2), which promote intrahepatic triglyceride accumulation by impairing lipid remodeling or very-low-density lipoprotein (VLDL) secretion [16,17]

References Brass, E

I recommend testing thyroid hormone levels every six to 12 weeks while using complementary therapies, including root cause medicine, diet, or supplements that may optimize your thyroid function, improve the absorption of thyroid medications, and/or reduce your requirement for thyroid medications (you know, all the stuff I recommend on my website!), as well as when incorporating new lifestyle changes, to ensure your thyroid medication dosage is optimized or sooner, if you are showing any of the above-mentioned symptoms

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