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Interestingly, the gut-brain-kidney axis has significant implications for the development and progression of CKD, offering options for the management and treatment of the condition

In conclusion, the findings of this study indicate that all examined biomarkersinterleukin-6 (IL-6), C-reactive protein (CRP), and tumor necrosis factor-alpha (TNF-)may serve as valuable prognostic indicators for potential complications associated with diabetes

Important Note on the Evidence Base Important note on the evidence base: The preclinical AOD-9604 literature in obese mouse and Zucker rat models is consistent and reproducible

(PubMed) de Rooij BM, Boogaard PJ, Rijksen DA, Commandeur JN, Vermeulen NP