glp 1 did not work for me Weight loss with GLP-1 medicines does result in a disproportionate loss of muscle mass or function in obese mice and humans: Cell Reports Medicine GLP-1 Not Working? Here's Why

Former UK prime minister Boris Johnson wrote in the Daily Mail that he asked his doctor about taking semaglutide after he noticed some colleagues were suddenly thinner, who told him he was an "ideal candidate." "I must have been losing four or five pounds a week maybe more when all at once it started to go wrong

These pathways contribute to the regulation of food intake, glucose metabolism, and energy balance through the CNS-mediated effects of bile acids and their downstream signaling molecules

A clinical review in Mayo Clinic Proceedings notes that GI effects are common across GLP-1 and related therapies

And understandably, it's a time of confusion