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In essence, brain centers are lowering testosterone in obesity, said Sun Kim, MD, an associate professor of Endocrinology at Stanford Medicine who wasnt involved in the research

Results are usually best when the system is paired with a balanced diet, resistance exercise to preserve muscle and sleep management to reduce stress and cortisol mediated appetite increases

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411 Genetic studies have further reinforced this therapeutic rationale, as loss-of-function mutations in the APOC3 gene are associated with lower plasma triglyceride levels and a reduced risk of ASCVDs