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It's still important to eat a healthy diet and get regular exercise in order to achieve and maintain weight loss

Lower Circulating B12 Is Associated with Higher Obesity and Insulin Resistance during Pregnancy in a Non-Diabetic White British Population Low serum vitamin B-12 and folate concentrations and low thiamin and riboflavin intakes are inversely associated with greater adiposity in Mexican American children Serum concentrations of vitamin B-12 and folate were inversely associated with BMI

Its role is particularly important in protecting cells from oxidative stress, assisting in immune responses and supporting overall metabolic health

There are some studies implying that metformin might attenuate weight regain 2