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Macromolecular Chemistry and Physics

The exact mechanisms underlying these cardiovascular benefits are still being investigated but may involve a combination of improved blood sugar control, weight loss, and direct effects on blood vessels and the heart

Circulation Heart Failure 2010, 3: 244-252

Looking ahead, improving tissue- or cell-specific vector targeting, building high-throughput screening platforms for FAD-sensitive variants, and using patient-derived iPSC neurons for personalized preclinical testing will be pivotal in transitioning from experimental use to clinical implementation of integrated nutrient plus gene-editing therapies