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Serotonin syndrome following cardiac surgery

This forms a complete regulatory cascade:NNMT inhibition NAD+ elevation metabolic optimization This unique mechanism makes 5-amino-1-methylquinolinium injection a critical tool linking NNMT activity, nicotinamide metabolism, and systemic metabolic homeostasis, providing direct experimental support for exploring NNMT's role in energy metabolism

Future research should prioritize high-quality RCTs to establish the efficacy, safety, and clinical application of redox-targeted therapies

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