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The therapeutic efficacy of the nanodrug-anchored platelets will be evaluated in high-cholesterol diet-fed ApoE / mouse model of atherosclerosis, which is expected to significantly mitigate oxidative damage, modulate macrophage-driven inflammatory and immune responses, and reduce the recruitment of immune cells to the plaque sites, thereby contributing to plaque regression and fostering a more stable plaque microenvironment

Evaluation of oxidative metabolism and oxidative DNA damage in patients with obsessivecompulsive disorder

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Furthermore, ALA may work by blocking p53 from causing ferroptosis and by upregulating ferritin and ferroportin iron exporters, thus preventing folic acid-induced AKI [105]