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June 18, 2024

A milder, less common type happens in older infants and children Most patients with CACT Deficiency Disorder have a severe disease presenting within the first 48 hours of life as low blood sugar with ketonic bodies (hypoketotic hypoglycemia), high ammonia (hyperammonemia) levels in the blood, increased heart muscle (cardiomyopathy), and abnormal heart rhythm (arrhythmias), as well as skeletal muscle damage, liver problems, and low temperature (hypothermia) Neurological involvement, seizures, and developmental delay are also present

There is no equivalent dose of Orsema SC Injection 0.25 mg/0.188 ml tablet for Orsema SC Injection 0.25 mg/0.188 ml injection 1 mg Patients treated with Orsema SC Injection 0.25 mg/0.188 ml 14 mg tablet daily can be transitioned to Orsema SC Injection 0.25 mg/0.188 ml subcutaneous injection 0.5 mg once weekly