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The experiment was divided into two parts: Part 1, in which they were randomly divided into four groups: the WT group, the APP/PS1 group, the APP/PS1+ Dihexa (1.44 mg/kg) group, and the APP/PS1+ Dihexa (2.88 mg/kg) group, and Part 2, in which mice were divided into three groups: the APP/PS1 group, the Dihexa (2.88 mg/kg) group, and the Dihexa (2.88 mg/kg) + wortmannin (0.5 mg/kg) group

481 Neurodegeneration and abnormal nervous tissue development is, arguably, triggered by the invasion of amniotic fluid into the developing spinal cord and adding to the mechanical trauma