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Clinical formulations typically incorporate appropriate antioxidant buffers or maintain GHK-Cu concentrations within therapeutic windows (0.1-10 M) to optimize beneficial effects while minimizing pro-oxidant risks

A recent meta-analysis indicates a significant increase in seminal AOX and reduction of MDA following AOX therapy although significant inter-study heterogeneity was detected (112)

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3 correlate to visual color changes in the solutions as a function of the concentration of APTES and the extent of glutathione denaturation