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These compounds have been also tested in two now completed phase-II and -III trials for the treatment of systemic lupus erythematosus [310] and diabetes mellitus type 1 [311] respectively, showing progressive improvement in disease activity thereby opening the way for new treatment perspectives

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February 2025: Researchers published another study linking semaglutide use to the eye condition nonarteritic anterior ischemic optic neuropathy (NAION)